One person has died in a crash on State Highway 1 at Kekerengu, north of Kaikōura.
Another person had moderate injuries, police said in a statement.
The single car crash was reported to police soon after 3pm.
The road is now open.
Police ask anyone who witnessed the crash to contact them.
The latest death is the fourth road casualty this Labour Weekend.
One person died after a Bay of Plenty crash yesterday, one person was killed in a crash in Lower Hutt on Saturday, and one died after a crash west of Hamilton also on Saturday morning.
Seven people died on the roads last year during the Labour weekend holiday.