The UN is investigating evidence of a toxic gas attack on a rebel-held area of the Syrian city of Aleppo.
The attack in Aleppo reportedly left four people dead and many others injured. Photo: AFP
Rebels said the attack - which reportedly left four people dead and many injured - was carried out by government forces using chlorine gas.
The UN special envoy for Syria said a chlorine attack, if confirmed, would amount to a "war crime".
Footage obtained by the BBC shows people with breathing difficulties receiving treatment at a hospital.
Men, women and children are shown being fitted with oxygen masks by medical staff.
The gas is thought to have been chlorine dropped in a barrel bomb, said the Syrian Civil Defence - volunteer emergency response workers who operate in opposition-held areas.
UN special envoy Staffan de Mistura confirmed the global body's experts were investigating reports of a gas, believed to be chlorine, being dropped on Aleppo.
"There is a lot of evidence that it actually did take place," he told reporters.
"If it did take place, it is a war crime and as much it would require everyone... to address it immediately."
A man receiving treatment in hospital said he had been in the Zebdieh area of the city, where he lives, when two missiles landed near him and a group of friends.
"And a few minutes later, the smell of gas started spreading... and I felt my eyes burning and difficulties in breathing," he said.
"The smell was very strong - beyond any description."
A medic at the hospital said they had received a lot of casualties, who were "all ages", including children and elderly people.
"When we examined these casualties, we realised it was due to chlorine," he added.
Chlorine is a common industrial chemical, but its use in weapons is banned by the Chemical Weapons Convention.
A man receives treatment after a suspected gas attack on the Syrian town of Saraqeb earlier in August. Photo: AFP
Earlier this month, doctors and rescuers in Saraqeb in Idlib province reported that barrels suspected to contain chlorine gas had been dropped on the town.
It was not clear who was responsible.
Dr Abdel Aziz Bareeh, who works in Saraqeb, told the BBC that health workers knew it was chlorine.
"We were hit by it in the past and we are familiar with its odour and symptoms.
"We have 28 confirmed cases, mostly women and children."
In 2013, the BBC found strong evidence suggesting residents of Saraqeb had been subject to a chemical attack by government helicopters, something denied by the Syrian authorities.
Fighting has escalated in Aleppo in recent days, with rebels severing the government's main route to the west of the city.
The offensive sought to break a siege by pro-government forces, who encircled the east in July with the support of Russian aircraft.
Russia has announced a daily halt to hostilities between 7pm NZT and 10pm NZT from Thursday, to allow in aid.
But UN Emergency Relief Co-ordinator Stephen O'Brien said while that would be taken seriously, a break of up to 48 hours was needed to get enough aid in on lorries.
"We have supplies ready to roll - food rations, hospital supplies, ambulances, fuel for generators, water supplies and more.
"We will continue to use all available routes and mechanisms to do this, including cross-line and cross-border operations from Turkey."
A witness in Aleppo told the BBC there had not been any ceasefire on Thursday, contrary to what the Russians had said.
Earlier some of the last doctors in the rebel-held east of the city appealed to US President Barack Obama to come to the aid of the 250,000 civilians there.
They said that in the past month there had been 42 attacks on medical facilities in Syria, 15 of them on hospitals where they work.
On Monday, the UN said countless civilians had been killed or injured in Aleppo in recent weeks and hospitals and clinics had continued to be targeted.
Moreover, attacks on civilian infrastructure had left more than two million people without electricity or access to the public water network for several days, it added.
-BBC