The first consignment of Syrian chemical weapons materials has left the country on a Danish ship, escorted by Russian and Chinese warships.
Removing the most dangerous chemicals is the first step of a UN-backed deal to elimate Syria's chemical arsenal.
A previous bid to collect the materials was aborted after Syrian officials failed to deliver the toxic chemicals to the collection point in Latakia.
The hazardous cargo is due to be taken to Italy, where it will be loaded onto a US Navy ship and shipped to international waters for destruction in a specially created titanium tank on board.
The mission is being run jointly by the UN and the Organisation for the Prohibition of Chemical Weapons (OPCW).
Hundreds of people were killed after rockets filled with the nerve agent sarin were fired at three towns near the Syrian capital, Damascus, last year. The deal to remove chemical weapons from Syria was brokered by the US and Russia following the attacks.