An island within the Marlborough Sounds is now predator-free after a programme to get rid of mice, the Department of Conservation (DOC) says.
Operations Manager David Hayes said Maud Island had been an important wildlife sanctuary since the 1970s and is once more a safe haven for endangered native species.
He said mice were found on the island three years ago and a poisoning programme was started.
Mr Hayes said the mice were a threat to insect and lizard species, and even frogs.
He said two years had passed since a dead mouse was found on the island, which was enough time to confirm a successful eradication.
The government planned to make New Zealand predator-free by 2050.
By 2025 the project aimed to have all introduced predators eradicated from all offshore island nature reserves, and have 1 million more hectares of mainland New Zealand where predators were suppressed.