Torrential rains and flooding have killed more than 1100 people, including 380 children, in Pakistan, where army helicopters plucked stranded families and dropped food packages to inaccessible areas.
The United Nations has appealed for US$160 million (NZ$260m) in aid.
The historic deluge, triggered by unusually heavy monsoon rains, has impacted 33 million people, destroying homes and businesses, infrastructure and crops.
The country has received nearly 190 percent more rain in the quarter through August this year, totalling 390.7mm, than the 30-year average. Sindh province, with a population of 50m, was hardest hit, getting 466 percent more rain than the 30-year average.
At least 380 children were among the dead, Prime Minister Shehbaz Sharif told reporters during a briefing at his office in Islamabad.
'Monsoon on steroids'
"Pakistan is awash in suffering," UN Secretary-General Antonio Guterres said in a video message, as the United Nations launched an appeal to help the South Asian nation. "The Pakistani people are facing a monsoon on steroids - the relentless impact of epochal levels of rain and flooding."
Guterres will head to Pakistan next week to see the effects of the "unprecedented climate catastrophe," a UN spokesperson said.
He said the scale of the climate disaster commanded the world's collective attention.
Nearly 300 stranded people, including some tourists, were airlifted in northern Pakistan on Tuesday, a state-run disaster management agency said in a statement, while over 50,000 people were moved to two government shelters in the northwest.
"Life is very painful here," 63-year-old villager Hussain Sadiq, who was at one of the shelters with his parents and five children, told Reuters, adding that his family had "lost everything."
Hussain said medical assistance was insufficient, and diarrhoea and fever common at the shelter.
Pakistan army chief General Qamar Javed Bajwa visited the northern valley of Swat and reviewed rescue and relief operations, saying that "rehabilitation will take a long, long time".
The United States will provide $30m in support for Pakistan's flood response through USAID, its embassy in Islamabad said in a statement, saying the country was "deeply saddened by the devastating loss of life, livelihoods, and homes throughout Pakistan."
'Obligation to help'
Early estimates put the damage from the floods at more than $10 billion, the government said, adding the world had an obligation to help Pakistan cope with the effects of man-made climate change.
The losses are likely to be much higher, said the prime minister.
Torrential rain has triggered flash floods that have crashed down from northern mountains, destroying buildings and bridges and washing away roads and crops.
Colossal volumes of water are pouring into the Indus river, which flows down the middle of the country from its northern peaks to southern plains, bringing flooding along its length.
Pakistani foreign minister Bilawal Bhutto-Zardari said hundreds of thousands of people were living outdoors without access to food, clean water, shelter or basic healthcare.
Pakistan estimates the floods have affected 33m people, or more than 15 percent of its 220m population.
Guterres said the $160m he hoped to raise with the appeal would provide 5.2m people with food, water, sanitation, emergency education and health support.
'Not enough aid'
Sharif said that amount of aid would need "to be multiplied rapidly," pledging that "every penny will reach the needy, there will be no waste at all".
He feared the devastation would further derail an economy that has already been in turmoil, possibly leading to an acute food shortage and adding to skyrocketing inflation, which stood at 24.9 percent in July.
Wheat sowing could also be delayed, he said, and to mitigate the impact of that, Pakistan was already in talks with Russia over wheat imports.
General Akhtar Nawaz, chief of the national disaster agency, said at least 72 of Pakistan's 160 districts had been declared calamity-hit.
More than two million acres of agricultural land were flooded, he said.
Bhutto-Zardari said Pakistan had become ground zero for global warming.
"The situation is likely to deteriorate even further as heavy rains continue over areas already inundated by more than two months of storms and flooding," he said.
Guterres appealed for a speedy response to Pakistan's request to the international community for help, and called for an end to "sleepwalking towards the destruction of our planet by climate change".
- Reuters