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Tuberculosis is the leading cause of death from infectious disease in Papua New Guinea.
Another 5,000 people are expected to die this year while another 40,000 will become sick, according to a civil society group that works to reduce TB infection, B4H, or Business for Health.
B4H, which works with private businesses, wants to use this Sunday's World TB Day to highlight the reality PNG faces.
Principal Ann Clarke told RNZ Pacific's Don Wiseman strong leadership on the matter is needed across the country.