State Highway 6 through Kawarau Gorge in Central Otago is down to one lane after fresh rockfall.
Waka Kotahi said the slip happened near the Cadrona-Roaring Meg Pack Track about 4pm today.
Motorists should expect delays and are being asked to drive with extra care.
Waka Kotahi is urging people travelling on the route to check its travel alerts page for the latest updates.