Israel's military on Friday called for all civilians of Gaza City, more than 1 million people, to relocate south within 24 hours, as it amassed tanks ahead of an expected ground invasion after a devastating attack by the militant group Hamas.
"Now is a time for war," Defence Minister Yoav Gallant said as Israeli warplanes continued pounding Gaza in retaliation for the weekend attacks by Hamas militants that killed more than 1300 Israelis, mostly civilians.
The Israeli military said it would operate "significantly" in Gaza City in coming days and civilians should only return when advised. More than 1500 Palestinians have already been killed in retaliatory attacks.
"Civilians of Gaza City, evacuate south for your own safety and the safety of your families and distance yourself from Hamas terrorists who are using you as human shields," the military said.
"Hamas terrorists are hiding in Gaza City inside tunnels underneath houses and inside buildings populated with innocent Gazan civilians."
A Hamas official urged citizens not to fall for what it called "fake propaganda". Its military wing later said that 13 among scores of people it captured from Israel had been killed in the latest Israeli air strikes.
The Palestinian envoy to Japan accused the Israelis of seeking to completely destroy Gaza while the United Nations said it considered it impossible for such a movement of people to take place "without devastating humanitarian consequences".
Israel's ambassador to the UN, Gilad Erdan, described the UN response to Israel's early warning to the residents of Gaza as "shameful".
Israel has vowed to annihilate the Hamas militant group which led Saturday's attacks and said Hamas tunnels, military compounds, senior operatives' residences and weapons storage warehouses were among 750 military targets struck overnight.
A ground invasion of the narrow and densely populated Gaza Strip, home to 2.3 million people, poses serious risk, with Hamas threatening to kill its hostages.
Hours after the Israeli evacuation call, there were no signs people were leaving Gaza City, where dozens gathered at the al-Shifa Hospital, vowing to stay put.
Pro-Palestinian protests were expected around the world and the United States and regional leaders planned meetings amid fears that conflict could spread.
The UN humanitarian office (OCHA) said more than 400,000 people had fled their homes in Gaza and 23 aid workers had been killed.
The International Committee of the Red Cross (ICRC) said generators at hospitals in Gaza could run out of fuel within hours and the UN World Food Programme (WFP) warned food and fresh water were running dangerously low.
"The human misery caused by this escalation is abhorrent, and I implore the sides to reduce the suffering of civilians," ICRC regional director Fabrizio Carboni said.
The UN Palestinian refugee agency (UNRWA) said it had moved its central operations centre and international staff to Gaza's south and urged Israel to spare its shelters.
'Riddled with bullets'
Seeking to build support for its response, Israel's government showed US Secretary of State Antony Blinken and NATO defence ministers graphic images of children and civilians they said Hamas had killed in a weekend rampage in Israel.
Blinken said they showed a baby "riddled with bullets", soldiers beheaded and young people burned in their cars. "It's simply depravity in the worst imaginable way," he said.
Like others across the globe, Blinken urged Israel to show restraint. He also reiterated America's support, saying: "We will always be there by your side."
On Friday he was due to meet Jordan's King Abdullah and Mahmoud Abbas, head of the Palestinian Authority in the Israeli-occupied West Bank.
Seeking to stop spillover from the war, he also planned to visit key allies Qatar, Saudi Arabia, Egypt and the United Arab Emirates - some with influence on Hamas, an Islamist group backed by Iran.
Iran's foreign minister met the head of the powerful Hezbollah movement, Hassan Nassrallah, in Lebanon, where there have been cross-border clashes with Israel since the weekend, Lebanese media outlets reported.
The foreign minister of Turkey, which has offered mediation over Gaza, talked with his counterpart from the UAE, a Turkish foreign ministry source said, and will visit Egypt on Friday.
The US military is placing no conditions on its security assistance to Israel, US Defense Secretary Lloyd Austin said, adding Washington expected it to "do the right things". Austin was due to meet Israeli Prime Minister Benjamin Netanyahu in Israel on Friday.
Safety concerns prompt security measures
The United States and Japan were among countries offering charter flights for their citizens wanting to leave Israel.
Police in Paris used tear gas and water cannon to break up a banned rally in support of the Palestinians.
Some Jewish schools in Amsterdam and London were set to close temporarily due to safety concerns and police in New York and Los Angeles stepped up their presence around synagogues and Jewish community centres.
New Zealand has also closed its Jewish school and some synagogues.
The Arab American Anti-Discrimination Committee, an Arab advocacy group, said on Thursday that FBI agents had visited mosques and US residents with Palestinian roots, calling it a "troubling trend".
In Jerusalem, scores of Israelis gathered at the Mount Herzl military cemetery to bury their dead.
"I could not imagine this is how it would end," one mourner said.
In Gaza's main southern city Khan Younis, dead were being buried in empty lots, like the Samour family, killed on Wednesday night in a strike that hit their house.
"This war is harsh beyond imagining," said Ibrahim Hamdan, who has worked through repeated wars since becoming a rescuer in 2007.
Gazans, mainly descendants of refugees who fled or were expelled from homes in Israel at its founding in 1948, have suffered economic collapse and repeated Israeli bombardment under a blockade since Hamas seized power there 16 years ago.
A peace process meant to create a Palestinian state collapsed a decade ago and Israel's right-wing government has cracked down in the West Bank and talked of seizing more land. Palestinian leaders say this left the population with no hope, strengthening extremists.
- This story was originally published by Reuters