One person has died and another person is seriously injured following a collision between a van and a truck near Blenheim.
Emergency services were called to the crash on SH6 between Lamberts and Camerons roads near Kaituna shortly after half past one this afternoon.
The road remains closed between Rapaura Road and Queen Charlotte Drive, and diversions are in place.
Light traffic can detour via SH1 and Queen Charlotte Drive between Nelson and Picton, but freight will need to go via SH63.
Meanwhile, five people have been injured in a crash involving a number of vehicles in the Christchurch suburb of Hornby.
The collision happened at the intersection of Main South Road and Goulding Avenue shortly after 2pm this afternoon.
Ambulance officers treated five patients with moderate injuries, three people were taken to hospital.