Samoa's principal film censor has banned the movie, Angels and Demons, which was due to screen in Apia later this week.
The principal censor, Lei'ataua Olo'apu, says the film is critical of the Catholic Church and that is why he is banning it.
The movie, based on the best selling book by Dan Brown, is currently the highest grossing movie around the world.
The censor, who is Catholic, says the ban will avoid any religious discrimination by other denominations and faiths against the church.
Three years ago, Samoa banned the movie Da Vinci Code, which was based on the book of the same name, also by Dan Brown.
Lei'ataua says the management of the only cinema, the Magik Cinema, has accepted his decision and will not appeal the decision.