Prince Andrew is to face a civil case in the US over allegations he sexually assaulted a woman when she was 17.
Virginia Giuffre is suing the prince, claiming he abused her in 2001.
His lawyers said the case should be thrown out, citing a 2009 deal she signed with convicted sex offender Jeffrey Epstein. But a New York judge ruled that the claim could be heard.
He has consistently denied the claims. Buckingham Palace said it would not comment on an ongoing legal matter.
The motion to dismiss the lawsuit was outlined in a 46-page decision by Judge Lewis A Kaplan of the United States District Court for the Southern District of New York.
It means the case against the Duke of York, 61, could be heard later this year.
In court documents, Giuffre said she was the victim of sex trafficking and abuse by late billionaire financier Epstein.
Part of her abuse involved being lent out to other powerful men, she alleges.
Prince Andrew, the Queen's second son, said in an interview with BBC Newsnight in 2019 that he had no recollection of ever meeting Virginia Giuffre, and her account of them having sex "didn't happen".
His lawyers had argued that Giuffre agreed in court in 2009 not to sue anyone else connected to Epstein when she settled her damages claim against the billionaire sex offender.
During a virtual hearing they said the Duke of York was a "potential defendant" as defined by the agreement and the case "should be dismissed".
Giuffre's lawyer said only the parties of the settlement agreement could benefit from it, and not a "third party".
In his decision, Judge Kaplan said the agreement "cannot be said" to benefit the Duke of York.
He said his ruling did not consider the "defendant's efforts to cast doubt on the truth of Giuffre's allegations, even though his efforts would be permissible at trial".
He added: "In a similar vein and for similar reasons, it is not open to the court now to decide, as a matter of fact, just what the parties to the release in the 2009 settlement agreement signed by Ms Giuffre and Jeffrey Epstein actually meant."
Prince Andrew withdrew from public duties soon after his 2019 Newsnight appearance.
He used the interview to re-iterate his denials of Giuffre's claims and explain his one-time friendship with Epstein and the financier's girlfriend Ghislaine Maxwell.
In December, a jury in New York convicted Maxwell of procuring teenage girls for Epstein.
- BBC